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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a1232cb5b38ce07e91aa7afc37496c7b6729829bb088ade99b8af8b5f417f9' 
  AND token = 'FWAVPdpd4eVC4d/1Bs7TnPOzdrhhwbAKcG2zrkDab2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}