SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8deea442a0f295aca8a9cc8e13e5bce3f8e3c5a339552f2bbe6a634e9f2471' 
  AND token = 'UIM9GQrYEHf5g8cbYBJlcFDVymoeoNNUMrlb5snt9OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}