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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd47e0e0a15aa91c1ba245cf4ba1bf8be57150f6caec60ee5443e60275b678914' 
  AND token = 'jNI2xKaqVmytQN86kx9uVA5JE2eC3DwDm7zem2OlNOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}