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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a65820d49697e1d497e13faebb27a3ec5dc7ffdf7bd3893ce16281a7e27a1e4' 
  AND token = 'PxSBL56KDAUQfyA36oONDuoZx4Ps6T9IcQemPWA/saM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}