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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfa51c420015fb33b8d7bab31da06f182f38a5ffe34da21c456140d016b8de37' 
  AND token = 'GuTNXd5Bf3KynU2MAYBCaqs5WGnI/vtZ9a2hLWgcm40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}