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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79f4a78e429e1425803fb61e1b4ac33cb50c401603c8c586c59e20c007997f68' 
  AND token = 'u/w8fDCl8lSkCMrVKlFmic7sV3NpOsS1C5zkVdg5DP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}