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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c887778c62bc0c4aa50d03b148432f487d4d482f643e21bc0a7ddb9230051fb' 
  AND token = 'cqMG5mvCFU1OrQ8rqQDNm7GPi/EMWvoYR5M4dqvTMUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}