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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427e1d12fca2cdb54000e38a7890f2012b8df0a3d55cb31f6bb27bf3256de31a' 
  AND token = 'u7hXW0cgQAutgf8SioEDggS3bssSkH8PMsN6W7ipaWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}