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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60ac0620dc00d0187118fb6fa80e3e4a593214c556fe643b6ad9f3bebf643899' 
  AND token = '4v7WK1W6/Eo/7nkFsxfd8UeyD4OCfhNSA0NdT9YtSzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}