SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b64f99f24280b08f9729fc8ae0a6e87039a03ec70c68d8f441341ff84725bb2' 
  AND token = 'OdfvB4dl/Bvheqqq7BQkni5rArvYhbHsLFOB5sH9fDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}