SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0291b8847c6f0d8f035c3bae93ac475f1fb95b22bdcfa57b9696df4554e5b64a' 
  AND token = '0Wj4YjmblW3NnRz2upKEI3yoJ4A+4wfcNn6ayzKRuLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}