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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0e7b49e21d33dc6ba1c30bf807a512b24f3520f67e65cb6a8415beb6ce4164' 
  AND token = 'ECZRqGWIkR+RiwQ7KcyyUf0vP27WKzR2KJVky7wYB0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}