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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051ce218ffc92d5160ef0b4b1c93aa0dcef34d045f90ce9bc860310fa358dbc8' 
  AND token = 'GJIt5L1EBbyHt5fDcOSu0sX27xd8Xkuue41tBUQu8Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}