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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019529d47103e3de9b8b05a5628b9328e7b73b5f02b4e0080c867201c479970a' 
  AND token = 'chRjDMGgMO+FLYCNdSr/lgnFgb6o/8rPfUOg+OwRyiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}