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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c2bd86215b01e81e9a0c707f62fb4d3fbcfcf8d49f8d6963146ecf03b42f23' 
  AND token = 'PSFbfyqIgOcJvbqb2WiCjzcybNaaRMA/wTNb5D1Ij78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}