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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c80500de93c5e284ac3a0d2d7a9af2264ff5ad41bebdaa950e2ea753c6fd62' 
  AND token = 'lRFA/KmijSNruZ9CgzicyORpdrOh+JF1z9Ek/+rzXa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}