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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e003e44a8d5c572befe7f3bd50921e903a8877c2eb733212aad604ace1053afc' 
  AND token = 'ROuY+M98KHz7VH5tTtsoyONA1L/DJA+Ghr+N0tzq/Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}