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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d3b251aab0b191a08b3f0b63464fec6d72da90701675a3576b84ab279a8626' 
  AND token = 'El7OfSDfD7PsJTfbTFn1LSRFDSHbrlYC1QZNJJUEs2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}