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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4ec820adb8d5a2cdc36650329ecff97d55ee455669a7e99ddb914572eabafdd' 
  AND token = 'HXYV7CwE2Ks1G8owk3ZWkW+zitzDOPXBPTHFRZXDSpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}