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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40d6d875800f67b42b9fe45d7365b8947b2148985ccc86db99c8667bf4dbc56' 
  AND token = 'DCyC2Uoq19LhkhLa9SxOWcIlJoKaReeiQIWzGC+kFCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}