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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd267bb07f4024fd33a10f3061ee3c403bc0b88354b5f0ff57e8c48234af92ab3' 
  AND token = 'LCTCJLmvyopYc5C3TGJMYYNv9zBoaq6Owbs+Ec/b//4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}