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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c750cd7c0cca272678406a8c53798449bade88c00a8a10d04097b3bad2394a' 
  AND token = 'sh6sBE7TcaOh+RyrgLBBCLIZ9VnaXW2JUO3XGXvCHYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}