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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af57c4aa7748f8a77e8330a1c75174979af096860469d4240e8c7dde9ce2cd66' 
  AND token = '06fPMv4t8a6X6bF3zIucet+Ctvf2eCBg2cc9bPDGqaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}