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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c02ca2473e5f625a1e13189866a71b30a7195bd15b36d47ed272bdc4f5fcb4e' 
  AND token = 'NRv9qsRUe4T6EmsjwrwVOEdRBcl9zGFl3sGsUiw3yTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}