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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00868d59635b712bcd7e535abb141e77c84e1e28e2e059875eb4a75d7c42875' 
  AND token = '+pVGFehGYix0+yQRexxZdAMPAQU+iCTATrxJw9G8ivE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}