SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e1721ec396c366e76076e51a3bf0218bbf47379c57f25e58d1259aed6659db' 
  AND token = '+VbU1gTl3kftMex5eCrXyDVP8NtZ0d1w7FpMBZOnxBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}