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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2adae6a200ffac864059ec9c688003aa219441fe84da8272eb932db3ac96e70' 
  AND token = 'LWUBFZluns46xY4xFRh/p/UpuCCbuEGEDQGZf1l6ZNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}