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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25b9698ea49860661a7c985d4a0daa278fed1c858cf8aef186e6fdd8ccf44e7' 
  AND token = '+OZhMhcd6yztmuqbxoUDkBYH6fYcJJUp2VqkEwEcPO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}