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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f217db288ba3cfff0be61909d6fbad0e5fe9d19624d3d234dbe958f97f266b5f' 
  AND token = '+O9wfMS7xirQQHKX2cd0n7qwhIpwH1FcU4qvLBcZuHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}