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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c12e01b7a26654fed1fb7f9b98cb0f768a504ba7136ab3657e750b5237f77c' 
  AND token = 'mVYZV/gxoZRANZtoZ1jh2QPkfbRSH8oepgfgq1S8Pkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}