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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818364e5ea7d8f1decbf7de2767da7058bff4fe56b8bf0afc3dcde8dc04b00de' 
  AND token = 'ZzM0HmHERy2PPInO+4oCu6AH4VeprlhjdLH0FqW47YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}