SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad507cb77e2cb63dd15153c9cec825f0dc57a54d4d0a5e4e145a6b7c70ba727' 
  AND token = 'WGnT0TqqPcEr3aTRiF/X7lLBJeFv87cGAauXJGRk2x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}