SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e55836415add648666efe9e172fbd65b8271efcb88e2c0573e4654257846cea' 
  AND token = 'ftoOP5cENxXUPwvX5W3dOplbps77M1HostPyJQE3UGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}