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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac6ff9eb5b9f773bdcee48c48b1ad7edf04c1b175359b6b8ac5c775dc9ac6c66' 
  AND token = 'HtS0h1vN5yA9KKhfkkZMM9g6moAOipi040O7F+Z84k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}