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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e463a83a0f8adb20878008cd7a04c136ce205e300ef6fc51c6e8eff65d27507' 
  AND token = 'ppZ5hoKH83CEyzVcCfMvDBsb8uAU9uloRLqRKY7a4Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}