SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7de9a96d0bed790a2e42a348cb17567942df063d7d3649ac266fafa90cd08f2' 
  AND token = 'RqmRsj7CqFItwKnCa4b3sLYNrDKAZySEj+1OyPXkhmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}