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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95cb027763319867c62fa8719936481bfb5aecad7b64da0820d6810e2f90970f' 
  AND token = 'FDV+qjG0UGHXXfJO7DMH1921Ue2AkO9VWgbpdbKesCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}