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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c56786c6acf9bba8db56bf602e9dde912b300c6ad89fa176be19eb742c4a8615' 
  AND token = 'XeQPF3Hgi2OT+DbeAaLa4C++/WuAXBCWmhkAPzWpBEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}