SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa09c85c9181e08323f722bdf0eeea9623c241a8f96eafb3989d721f5dcf0384' 
  AND token = 'ZGVf49fqJude2z2okZm1JWDLcpobsWM4fB0a/e30Hig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}