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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3f50c90721c327074f7952a5fb7c82499559f35a48ac9b853f6e9568f764511' 
  AND token = 'DzMT73Tn2lae9a6dSYPah4dC6oeCwcU7jy0iBs6po7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}