SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '919246f71f74f54c5e8bf4421429ae204560cfa82e65873364bce4e3bb3777e1' 
  AND token = 'MjppzF8L1oPkL1C9gKhkrWz+OHTd89lZ4HEqqQ1KUCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}