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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e808821f6b52fe8807e1f906be86d1b474e537b0f8a459adc3161d5519b572a5' 
  AND token = 'PpcwKzRd42dnSwNOMATErT1qMOIEy+MSt6olLMQh1bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}