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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3925dade724184a2045964eb9739446e88bead555d6cc1e50929227a4a41a072' 
  AND token = 'jnUr53rOshXkHpk3RomgUImIZoGG9BiepVSA8ncXc3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}