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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c44a469a2857f20f99a727c4a9625901d5b47ff625d394b19aa04f17f2c14b' 
  AND token = 'n7ml7hYuk/o2lEfygTo2hXtqYLi+l4TcSHEfgY380ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}