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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450be8d849f1366c0eaf6f20402e1fe6670ef706bc31035da2a6f6d8bb18f4b2' 
  AND token = 'T/KwRdkZ19ANB1VuLid3T2pjoIk+bTakK+p7uh7aLJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}