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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6515cea0f70dde7edc3377c5673e23c0c1dc7f0ee582f7454b617d0e2bbadade' 
  AND token = 'QSZW2n+MY+fl4EiL5jnhv/asETz3DaBotDGLHuqVwnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}