SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ce310ff787591140ad81764e86fa1bf34073372025930d42059d2f641c7293' 
  AND token = '6NvqLaIK2dNPZymHn1pq8uIGVakGtp+vDeddLEe/ZOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}