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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc81276cf98df7a0c0d613a937424ab1e57c2d3eb808ab680b2c5f95abb85a4' 
  AND token = 'uzPoG+aFM33qu1RbC8t7PHpHULKzRthRcY9SpnMWPDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}