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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e669401d8ca3fcf0bd7ab3f97710d3239d9e8ba41d54a86d8d4f4707c7f6c78' 
  AND token = 'u+1LQI8V4EJRCHDBSyNYSGifJaIzJiMgF2t1T9pk7PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}