SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8851959294b70ed77be06ff71cf31578e84b5c2c4ac5eb887af9eeb55ad7b6' 
  AND token = 'Hl7ZWJtK7NvEYqcinbZlNh4Dj6WIB+S7rwiaOYV2jEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}